1437. Family Duty and Safety Linked to Overcoming Attitudinal Barriers to Adult Pneumococcal Vaccination in Disparate Populations
Session: Poster Abstract Session: Pneumococcal Vaccines
Friday, October 5, 2018
Room: S Poster Hall
Posters
  • PNA Vaccines_IDWEEK2018_PosterFINAL.pdf (5.4 MB)
  • Background: Minority adult populations are at a higher risk for invasive pneumococcal disease and also have significantly lower vaccination rates when compared to the general population. Ingrained attitudes are a significant barrier to receipt of pneumococcal vaccine in these disparate populations, and therefore we tested targeted informational messaging to overcome these.

    Methods: A survey instrument of attitudinal questions related to pneumococcal vaccination was administered via YouGov, an online public national survey house in 2017. Socioeconomic information was captured and linked to baseline Likert scale attitudinal question responses. Respondents were randomly assigned into subsamples that received different science-based messages that included information on pneumococcal vaccines related to: pneumonia prevention, fatality/consequences, vaccine safety information, family duty/safety, and a combined vignette including all of these. Because of the random assignment, any differences observed in the respondents’ outcomes across subsamples can be attributed to the messages. Descriptive statistics were used to compare the persuasive effectiveness of these messages to conventional vaccine information across racial and ethnic groups.

    Results: A total of 2,608 respondents, 1327 (51%) white and 1281 (49%) non-white (over-sampled) were represented. Of the total respondents as well as in white, and non-white respondents, the combined vignette was associated with positive coefficients of b=0.26, b=0.24, and b=0.32, respectively (p-values all <0.05). In whites, the vaccine safety information and family duty/safety also had significant coefficients b=0.24 (p=0.012) and b=0.24 (p=0016), respectively. In non-whites, family duty/safety was the only additional message with a significant coefficient b=0.25 (p=0.007).

    Conclusion: In this survey assessing attitudes towards pneumococcal vaccination across racial and ethnic subpopulations, the disparate population were persuaded to receive the vaccine only when family duty and safety were linked within the informational messages. Future studies implementing this informational messaging strategy should be performed to validate this finding.

    Maria-Stephanie Tolg, PharmD1, Marc Hutchison, Ph.D2, Brian Krueger, Ph.D2, Katherine Orr, PharmD3, Jennifer DeAngelis, BA3, Aisling Caffrey, PhD, MS1,3 and Kerry LaPlante, Pharm.D., FCCP, FIDSA1,3,4, (1)Providence Veterans Affairs Medical Center, Providence, RI, (2)Political Science, The University of Rhode Island, Kingston, RI, (3)College of Pharmacy, University of Rhode Island, Kingston, RI, (4)Division of Infectious Diseases, Warren Alpert Medical School of Brown University, Providence, RI

    Disclosures:

    M. S. Tolg, None

    M. Hutchison, None

    B. Krueger, None

    K. Orr, None

    J. DeAngelis, None

    A. Caffrey, Pfizer Pharmaceuticals: Grant Investigator , Research grant . Merck: Grant Investigator , Research grant . The Medicines Company: Grant Investigator , Research grant .

    K. LaPlante, Merck: Grant Investigator , Research grant . Pfizer Pharmaceuticals: Grant Investigator , Research grant . Allergan: Scientific Advisor , Honorarium . Ocean Spray Cranberries, Inc: Grant Investigator and Scientific Advisor , Honorarium and Research grant . Achaogen, Inc.: Scientific Advisor , Honorarium . Zavante Therapeutics, Inc.: Scientific Advisor , Honorarium .

    Findings in the abstracts are embargoed until 12:01 a.m. PDT, Wednesday Oct. 3rd with the exception of research findings presented at the IDWeek press conferences.