47. Common Gastrointestinal Pathogens Identified Using the Biofire FilmArray Gastrointestinal panel at a Military Medical Facility
Session: Posters in the Park: Posters in the Park
Wednesday, October 3, 2018: 5:30 PM
Room: N Hall D Opening Reception and Posters in the Park Area
Background: Gastrointestinal (GI) illnesses are common infectious causes of morbidity and mortality worldwide. Patients are often treated conservatively, but empiric treatment may also include antibiotics. Stool and viral cultures are diagnostic gold standards, but are time intensive and result in delays in therapy. Often an etiologic organism is often not identified, resulting in inadequate or inappropriate treatment. A gastrointestinal panel (GIP) by Biofire diagnostics approved by the Food and Drug Administration can identify 22 GI bacteria, viruses, and parasites. We determined overall and monthly identification rates of common GI pathogens from William Beaumont Army Medical Center (WBAMC) using this panel.

Methods: We performed a retrospective lab review of Biofire Filmarray GIP results from WBAMC dating from November 2016 to May 2017. Descriptive data analysis was applied involving proportions (percentages), means, and other summary statistics.

Results: Population studied was predominantly male (69.5%). Thirty eight percent and 28% of the total population were aged from 19 to 50 and 51 to 71 years old, respectively. One hundred ninety-seven total tests were evaluated over this time period, with a 45.2% positive rate. The 5 most identified pathogens were Clostridium difficile (29% of all positive tests), Enteropathogenic Escherichia coli (EPEC) (14.6%), Norovirus (25.8%), Sapovirus (15.7%), and Rotavirus (12.3%). Positive tests for C. difficile, Norovirus, and EPEC were stable through the time period analyzed. Sapovirus positive results decreased during this time period, while Rotavirus increased towards the spring/summer season. No Escherichia coli O157, Enteroinvasive E. coli (EIEC), Enterotoxigenic E. coli (ETEC), Plesiomonas/Shigella, Vibrio or Yersinia species were identified.

Conclusion: Positive results for Norovirus and Rotavirus followed trends nationally reported to the Centers for Disease Control (CDC). Trends for Sapovirus and EPEC correlate with previously reported increases during the spring/summer time period. Clostridium identifications remained stable likely due to association with hospitalization and antibiotic use. Continued surveillance is needed, particularly with bacterial species, given their propensity for significant morbidity and mortality.

Edgie-Mark Co, DO, PhD1, Aaron Brockshus, MD2, Ellecia Rainwater, MD2, Rupal Mody, MD3 and Jeff Sherwood, MD3, (1)Medicine, William Beaumont Army Medical Center, El Paso, TX, (2)Medicine, William Beaumont Army medical center, El Paso, TX, (3)Infectious Disease, William Beaumont Army Medical Center, El Paso, TX


E. M. Co, None

A. Brockshus, None

E. Rainwater, None

R. Mody, None

J. Sherwood, None

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