Methods: A retrospective cohort of TKA PJI treated with two-stage exchange was identified by query of hospital coding records from 2009 to 2014, with subsequent chart review. Collected data included demographics and comorbidities, duration of symptoms, implant age, and pathogen. All cases met Musculoskeletal Infection Society International Consensus criteria for PJI. The primary endpoint was defined as prosthesis retention for 2 years from reimplantation. Descriptive statistics were completed using the Fisher’s exact test for categorical variables and the Mann-Whitney U test for continuous variables.
Results: 159 patients who underwent 2-stage exchange for TKA PJI meeting MSIS criteria were identified. 116 patients (73%) remained infection free after two years of observation. Neither of the major criteria [presence of sinus drainage (p=0.6); >1 positive culture (p=1.0)], nor any of the minor criteria (individually or in composite) reached statistically significant association with treatment outcome.
Conclusion: Individual MSIS diagnostic criteria, which have prognostic utility in TKA PJI treated with DAIR, are not powerful predictors of outcome of TKA PJI after two-stage exchange.
A. Nocon, None
G. Westrich, None
M. Henry, None