Methods: The National Inpatient Sample (NIS) was utilized to identify hospitalizations associated with pregnancy from 2002 to 2014. The aggregation of hospitalizations was stratified into two groups based on HIV status to determine if there were differences in demographic factors, complications, and mortality. All analyses accounted for the NIS sampling design.
Results: There were 39,404,956 pregnancy-related hospitalizations identified, of which 51,762 were also associated with a positive HIV status. There were differences in complications for those with and without HIV, which included eclampsia (1.27% vs. 0.45%; p< 0.001), preterm labor (11.81% vs. 6.41%; p< 0.001), gestational diabetes (0.92% vs. 0.38%; p< 0.001), group B strep (0.03% vs. < 0.01%; p < 0.001), and gram negative infection (0.07% vs. 0.03%; p= 0.013). After adjusting for mortality risk, calendar year, age, race and ethnicity, insurance, and zip-code level income, it was found that a positive HIV status was associated with a 91.1% increased odds of mortality (95% CI: 3.9% to 351.5%; p= 0.037).
Conclusion: As ART are readily available we expected better outcomes for our HIV positive pregnant females. Our results are concerning that there is such an increase rate of mortality and health disparity in HIV positive pregnant females. As this is a retrospective study there are limitation and further studies need to be conducted.
C. Destache, None
J. Horne, None
G. Gorby, None
R. Vivekanandan, None